Releasing the brakes to fight cancer
نویسنده
چکیده
U S President Richard Nixon declared “War on Cancer” in 1971, but it was not until 45 years later that his successor called the country to arms for the final battle. “For the loved ones we’ve all lost, for the family we can still save, let’s make America the country that cures cancer once and for all”, said US President Barack Obama in his last State of the Union address in January 2016. And, yes, he used the word “cure”, which is not easily said when it comes to cancer. ...................................................... “This hope for new treatments that could really cure cancer, rather than extend lifespan by a limited time, is fuelled by new discoveries in cancer immunology.” ......................................................
منابع مشابه
A current perspective on cancer immune therapy: step-by-step approach to constructing the magic bullet
Immunotherapy is the new trend in cancer treatment due to the selectivity, long lasting effects, and demonstrated improved overall survival and tolerance, when compared to patients treated with conventional chemotherapy. Despite these positive results, immunotherapy is still far from becoming the perfect magic bullet to fight cancer, largely due to the facts that immunotherapy is not effective ...
متن کاملReleasing the Brakes on Cancer Immunotherapy
This year's Lasker∼DeBakey Clinical Research Award goes to James Allison for discovering that antibody blockade of the T cell molecule CTLA-4 unleashes the body's immune response against malignant tumors. This has led to development of multiple "immune checkpoint therapies" that are prolonging and saving the lives of thousands of cancer patients.
متن کاملHelping Cancer Patients to Fight with Infection
نوتروپنی در صورتی که منجر به شوک عفونی گردد، میتواند باعث مرگ بیمار شود مقابله با عفونت، شامل بررسی دقیق، مراقبت های پیشگیری کننده و مداخله به موقع می باشد. بیماران سرطانی بستری در بیمارستانها، اغلب در معرض خطر عفونت قرار دارند. بویژه اگر احتیاج به درمان شدید با روش های تشخیمی داشته باشند. هرگونه عفونت می تواند تهدیدی برای زندگی بیماران دارای نوتروپنی محسوب شود.
متن کاملA Comprehensive Fuzzy Multiobjective Supplier Selection Model under Price Brakes and Using Interval Comparison Matrices
The research on supplier selection is abundant and the works usually only consider the critical success factors in the buyer–supplier relationship. However, the negative aspects of the buyer–supplier relationship must also be considered simultaneously. In this paper we propose a comprehensive model for ranking an arbitrary number of suppliers, selecting a number of them and allocating a quota o...
متن کاملBeyond CTLA-4 and PD-1, the Generation Z of Negative Checkpoint Regulators
In the last two years, clinical trials with blocking antibodies to the negative checkpoint regulators CTLA-4 and PD-1 have rekindled the hope for cancer immunotherapy. Multiple negative checkpoint regulators protect the host against autoimmune reactions but also restrict the ability of T cells to effectively attack tumors. Releasing these brakes has emerged as an exciting strategy for cancer tr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2016